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Sirius satellite radio is a satellite radio service operating in the US, Canada and Mexico and is based in New York. It provides more than

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

125 radio channels out of which 55 are sports, news and entertainment channels. The most attractive feature of this radio is that all th

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e channels are commercials free.

Sirius satellite radio is broadcast over North America using 3 satellites. Some of the Sirius music cha

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nnels are included in DISH Network satellite television service.

Sirius satellite radio service was started in 1990. It has more than 4

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

illion subscribers. The company was named after the Sirius star.

There are over 125 channels available some of them are:

Pop/Hits. Si

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rius Hits1, Star Lite, Sirius Love, some channels for hits from 50s, 60s, 70s, 80s, 90s and today, Elvis channel and French songs channel.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Rock Channels. Classic rock channels for 60s, 70s, 80s, Hard rock, Alternative rock, Metal, Heavy metal, Punk, Hip-Hop, Reggae etc.

El

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ectronic/Dance Channels. These channels cover electronica, trance, disco and dance.

Hip-Hop/ R&B channels. These channels have, modern,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rogressive, old school Hip-Hop, classic and soul music.

Country channels. They cover country music, 80s, 90s, Classic country and outlaw

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

music.

Christian channels. They contain Christian rock, contemporary christian, Gospel music.

Jazz/Blues channels. They contain Moder

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n, smooth, classic Jazz, New age and Blues music.

Miscellaneous channels. There are channels which contain starndard music, classical mu

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

sic, latin and world music.

Entertainment channels. These have talk shows like howard stern show, blue collar comedy, stand up comedy, g

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y/lesbian entertainment, celebrity gossip, women talk radio, live trial proceedings, environment programs, Discovery, childrens channels,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

conservative channels, liberal talk, truckers talk, christian talk, family nets, Adult channels like playboy etc.

News channels. These

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

channels have sports news, world news, news of various states of the US, financial news like CNBC, ABC News, CNN, NPR, CBS etc.

Sports c

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

hannels. They include ESPN, Sirius sports, sports byline etc.

Purchase. The sirius satellite radio receiver is available in leading ele

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tronic stores or can be bought from sirius.com. The radio which are sirius ready can only access the sirius satellite channels after bein

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

g fitted with a sirius tuner and activation. The activation can be done online at 10$. The monthly subscription charge starts from 13$ a m

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

onth to 500$ for lifetime subscription. The radio channels are available 24 hours a day. These radios are being fitted in most cars avail

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

able in the US like Ford, BMW, Chrysler, Jaguar, Jeep, Lincoln, Mazda, Mercedes-Benz, Nissan, Toyota, Porsche, Volkswagen, Rolls-Royce etc

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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