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ArticlePedia - White Teeth at Home
Do you find yourself staring enviously at the smiles of Hollywood stars radiating out of entertainment magaz
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ines? You too can have a smile so brilliant. With the growing trend of teeth whitening, costs have gone down
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
and more products have become available, making the procedure easier than ever before.
Teeth whitening, al
Teeth whitening, al
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
so called teeth bleeching, was once an expensive in-office procedure that only the rich and famous could aff
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
ord. Fortunately for the rest of us, teeth whitening can now be done at home, with the help of a professiona
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
l. Many dentists are specially trained in teeth whitening techniques. Usually, they will mold a tray fitted
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
to your teeth. You squeeze teeth whitening gels into the trays and keep them in your mouth for a prescribed
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
amount of time each day. Over a period of a couple weeks, your teeth will begin to shine. These teeth whiten
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
ing systems may initially cost hundreds of dollars. However, once a tray has been made, it can be reused ove
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
r and over again; refills of teeth whitening gels are inexpensive. And a tray made specifically for your tee
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
th will perform better than a generic mold.
Some teeth whitening gels are safer and more effective than oth
Some teeth whitening gels are safer and more effective than oth
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ers. Most teeth whitening kits include gels containing carbomide peroxide; the percentage you should use dep
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ends upon the sensitivity of your teeth. Using a gel with too high a percentage of carbomide peroxide can be
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
painful.
While over-the-counter teeth whitening systems are available, they may not be as safe and effecti
While over-the-counter teeth whitening systems are available, they may not be as safe and effecti
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ve as those purchased from a professional. Some may burn your gum tissue, especially if too much gel is used
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
. It is important to ask your dentist for a recommendation.
Remember that teeth whitening does not work on
Remember that teeth whitening does not work on
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
caps, crowns, or veneers. Also, it will not make your teeth stark white but will instead give your smile a n
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
atural, cleaner, brighter look. Teeth whitening can only be done once every few months. To avoid further ye
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
llowing of the teeth, limit your intake of coffee, tea, colas, and red wine, which are known to stain enamel
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
. Using a teeth whitening paste in addition to the kit can also help you maintain your new, beautiful smile.
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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