ArticlePedia - Health and Fitness

Simply wanting to stop smoking is a large part of the battle to succeeding. Often knowing that cigarettes are destroying your health is not enough incentive. Y

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ou don't want to think about all the health problems that smoking can cause.

After all, between the physical addiction to nicotine and the psychological addic

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ion, the whole person, mind and body, is craving the next cigarette. With that strong pull encouraging you to the next smoke, the thought of getting cancer, ha

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ing a heart attack, or hurting your unborn baby might not be enough to make you decide to stop smoking.

That your health doesn't deteriorate with the first ci

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

arette encourages you to believe that smoking is not dangerous. Tobacco takes twenty to fifty years to damage your body with cancer or heart disease.

For a yo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ng person who is encouraged to start smoking at fifteen or seventeen that seems like a lifetime away. The sad thing is, by the time the damage is done it can b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

too late to quit smoking. They can end up dead of a heart attack at forty-five or dying of lung cancer at fifty.

How does one succeed in stopping the mind an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d body from continuing this addiction? You must deal with the body and the mind separately but at the same time. In other words, deal with the physical addicti

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

n with one technique and the psychological addiction with another technique all at the same time.

It's actually easier to deal with the physical addiction. Th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

re are patches, pills, and gums that you can use if you need them. Your doctor will be able to help you in this area by recommending products that can help you

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

body lose the desire for a cigarette.

The psychological addiction is more complicated to overcome. Everyone would rather experience pleasure than pain, and t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ying to stop smoking will produce pain. To the smoker, cigarettes produce pleasure.

Some smoke to have something to do, or because they believe it will calm t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eir nerves. They might associate smoking with a pleasurable experience, such as smoking with friends at the bar or while they play poker. They aren't smoking b

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

cause they feel the need for the nicotine, but because they associate smoking with a good time.

So how does one overcome the psychological addiction? Some pro

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fessionals suggest filling up the time you would normally be smoking with some other activity. The activity needs to be a positive one or it won't work.

Have

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

he activities planned out. Know exactly what you are going to do in place of smoking and be prepared for it.

Include times of regular exercise, meditation and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

breathing exercises. Believe you can stop smoking and surround yourself with people who will encourage you to succeed.

Most importantly, get rid of the idea t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

at life isn't worth living without cigarettes. That thought must not be allowed. Change that thought to "life is worth living without cigarettes." Instead of t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

inking that cigarettes are good, replace the thought with something like "cigarettes are killing me."

By changing your thoughts about cigarettes from positive

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to negative you will change your beliefs about them. When your beliefs change, then you lose the psychological craving for them and it's easier to stop smoking

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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