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As Christians, we know we need God in every aspect of our lives do we not? We need God to work on us because some of us are so spiritually immature that it is hard to distinguish Christians from non-Christians. Thus, God com

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

mands us to do certain things for our own sake – not His. God wants to teach us how to move beyond ourselves to others. God knows we cannot make it to His kingdom until we learn how to sacrifice our needs, our wants, and our

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

desires, for the good of someone else. In other words, until we learn how to love one another, even the unlovable. And, we can never love until we get rid of the anger.

Anger is a strong feeling of tension and aggressivene

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ss which arises when we feel threatened, frustrated, or wronged in some way. It is an emotion which charges up the entire body – produces enormous energy and sometimes spills out in physical violence or verbal aggression. If

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

not put in check, anger can destroy.

It is disconcerting that man seems out of touch and out of control. We are angry with ourselves, angry with God, angry with our parents, angry over lost opportunities to do something wor

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

thwhile with our lives, angry because someone we loved died, angry because someone rejected us; angry because we did not get the promotion we expected, angry because someone cut in front of us in traffic, angry because we ca

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nnot have our own way. Everywhere we look, people are being destroyed by their anger. People are angry and do not know how to deal with it in a mature way.

Anger destroys us. It destroys us physically, psychologically and s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

piritually. When we become angry our breathing increases and blood pressure is elevated, the heart beats faster, more adrenaline goes into the blood stream, blood is detoured away from our internal organs and redirect to our

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

muscles for strength, our digestive processes stop and our immune system suppressed. The eyes are dilated for better peripheral vision, the hands get sweaty and the mouth dries. In only seconds, we are transformed from a qui

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

et condition to an attack mode. If the anger persists, the body remains ready for action and eventually begins to break down physically.

Anger also affects us psychologically. When we are angry, we cannot think rationally.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

We cannot make logical decisions. We “fly off the handle” with the least provocation. We jump to wrong conclusions because our thinking is distorted. And, when our thinking is illogical, our behavior is inappropriate. We wil

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

l do and say things that are senseless and out of order. We will misplace our anger onto the wrong people, curse folks, talk about folks and stab folks in the back when all the time it is our anger that is destroying us on t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e inside.

Spiritually, anger will keep us out of God’s kingdom because we are not abiding by His word. Scripture tell us:

Ephesians 4:26-27
"In your anger do not sin” : Do not let the sun go down

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

while you are still angry, and do not give the devil a foothold.
Gal 5:22-23
But the fruit of the Spirit is love, joy, peace, patience, kindness, goodness, faithfulness, gentleness and self-control. Against su

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ch things there is no law.

James 1:19
My dear brothers, take note of this: Everyone should be quick to listen, slow to speak and slow to become angry

Psalm103:8
The LORD is compassionate and gr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

acious, slow to anger, abounding in love.

Romans 12:19-21
Do not take revenge, my friends, but leave room for God's wrath, for it is written: "It is mine to avenge; I will repay," says the Lord. On the contrary

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

"If your enemy is hungry, feed him; if he is thirsty, give him something to drink. In doing this, you will heap burning coals on his head." Do not be overcome by evil, but overcome evil with good.

Ephesians 4:30-32
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
>
And do not grieve the Holy Spirit of God, with whom you were sealed for the day of redemption. Get rid of all bitterness, rage and anger, brawling and slander, along with every form of malice. Be kind and compassionat
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
e to one another, forgiving each other, just as in Christ God forgave you.

Proverbs 15:18
A hot-tempered man stirs up dissension, but a patient man calms a quarrel.

God wants us to bring whatev
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
er problem, need, emotion or dilemma we are faced with to Him. This means that as soon as we get angry, we turn it over to Him. When we allow God to manage our anger, we discover that He transforms it into something positive

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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