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    God said, “Thou shalt not…” and we continue to tell God, “we will.” We continue to prefer the terminal disease of sin over the eternal love and glory of God who wants fellowship with
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    us. And, we are sinners by choice.

    We are sinners by choice because we consciously and knowingly refuse to do what we know we ought to do. We clearly see the road on
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    hich we ought to walk, but we refuse to walk it. We see the Christian fight in which we ought to engage, but we refuse to enter the conflict. We choose to go on and on in our sins. W
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    e understand this to be true as we witness its results everyday in our homes, our neighborhoods, our society, our nation and our world.

    Turn to the Word and on its very first pages
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ou will find burning warnings against defying and rebelling against God. In every book is a record of God’s battle and fight with sin. We hear it in the thunders of Sinai, the sobs o
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    Gethsemane, the agony of the cross. We hear it loudly reverberating all through the Word of God. David, when he sinned for a woman’s beauty, he fell from the pinnacle of Jerusalem t
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    o a nation inundated with wars. And as sin reach beyond his control, it made his son Ammon a rapist and his beloved Absalom a murderer.

    Sin is a divider; it separates us from God wh
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    wants us closer to Him. Sin makes us lose our love for God, Christ becomes unreal and the Bible a collection of myths. Behind every war that has ever been raged; in back of every ho
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    e that is permeated with abuse, hatred and jealousy; in back of every juvenile delinquent, every prison convict, every suicide and every dissipated man, is the black scourge of sin.
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

    When we look at our world and society, everywhere we turn we see the degenerative effect of man’s sins. Today, we are paying for the support of schools which act as if there is no G
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    d. Rarely do two individuals agree on what is morally right or morally wrong. We are adrift without answers. No single authority rules our conduct. We are free to be prejudiced or pr
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    miscuous, to cheat and chisel.

    The film industry portrays the depth of human dysfunction and violence: pornographic industry has become the leading sellers for home videotape viewer
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    s, abortions has mounted up to a silent holocaust of millions, illegitimate babies account for more and more births, incurable diseases such as AIDS have joined dozens of other such
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    iseases rampaging out of control. The first decade of the 21st century is plagued with rapidly growing alcohol and drug addiction bringing an epidemic of child abuse, spousal abuse,
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    amilies’ dysfunction, spiraling divorce, soaring crimes and so on.

    Man has chosen sin over and over again, rather than Christ. And as a consequence, the average man, woman and child
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    are in greater danger today than ever before, of becoming victims of the criminal onslaught. Whether day or night, at work or play, our basic right to personal security and pursuit
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    f happiness are steadily diminishing. Sin.

    But, as Scripture warns, God cannot and will not tolerate sin. He allows us to run up a charge account of sin; we can live any way we choo
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    e, we can do all the things we want to do. We can steal, cheat, lie, be immoral and live as we please for what seems to us as a long time. God may seem indifferent and we may think H
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    e is dead or asleep or non-existent. We may think God is forgiving and therefore we can sin to our hearts’ desire and that all will be well with our souls. But God is not mocked. We
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    an go on ignoring Him and living as though He does not exist. But our charge account of sin has its limit. And when we have reached the limit set by God; we will have to pay our debt


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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