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ArticlePedia - The Origin Of Phobias - What Makes Us Afraid
I am scared of Spiders and also, of being high up. Guess what! My mother was afraid of the same things, and so is my s
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
on. So I started thinking about this and I have come to realize that Parents, without meaning to do it, can actually ma
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
ke their children afraid!
Years ago, when humanity was new, children learned from their parents, about what was dangero
Years ago, when humanity was new, children learned from their parents, about what was dangero
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
s in their world. Parents would run from a snake, or a wild animal, with their children, and of course the children lea
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
rned to fear the snake too. We all have a response to fear built into our genes. Its called 'The Fight Or Flight Respo
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
nse'. Our bodies flood with adrenalin and our heart beats quicker, our breathing-rate increases to provide us with more
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
oxygen for what we intend to do. The question is... Do we run, or do we stay and fight?"
This response has kept humani
This response has kept humani
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ty alive, but there are times when the 'Fight Or Flight Response', occurs when it does not need to. Most spiders are ha
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
rmless and are more afraid of us than we are of them, but try telling ME that when I see one! My mother also screamed w
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
en she saw a spider and because I was exposed to that fear, it became MY fear as well. I am not blaming my Mother for t
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
his, but if she had realized what she was doing to me, maybe she would have tried to have her phobia cured.
Years later
Years later
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
I passed the phobia on to Steve, my son, and yet, like all children, Steve is not afraid of snow. Why is that? You wo
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ld think that children who have never seen the snow before might wonder what it is, and panic when its falling all aroun
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
d them, but they never do. The reason is that parents, no matter how old they are, remember the fun they had in the sno
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
w and automatically pass that fun and excitement onto their kids. Butterflies are another thing that children do not fe
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
r, but on the other hand, they may not like moths, because their mum's do not like them.
Of course, there are times whe
Of course, there are times whe
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
n a phobia occurs because of a traumatic event. If you have almost drowned, you may develop a fear of going in the wate
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
r. Phobias will always exist, but some are preventable.
We need to work on our own phobias, just as we work on our pre
We need to work on our own phobias, just as we work on our pre
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
udices. Like prejudice, fear is passed on, and can cause all kinds of problems. But now we know what the problem is, i
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ts up to us to do something about it, for the sake of the next generation. They will have enough problems to worry about
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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