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One of the major attributes of cars looked at by car buyers is their dependability. That is why car manufacturers are always looking for ways to imp

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rove their vehicle’s reliability. A typical car usually shows its weaknesses and become prone to breakdowns when it has reached a certain number of y

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ears in use. But car manufacturers count on the reliability of their vehicles during the early stage of ownership.

A reputation of a brand is at st

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ake during this stage and this would be if a vehicle exhibits poor quality during the early stages of ownership, it will of course give the vehicle’s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

manufacturer a bad reputation. Some of the most dependable brands are Lexus and Honda while Ford, Toyota, and Nissan are not left far behind.

In a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

recent study conducted by the RDA Group, it has been found out that the quality of Ford’s vehicles is equal to that of Nissan and Toyota vehicles. T

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

he said study was conducted for the Ford Motor Company. It is conducted to give consumers an idea which brand offers the best dependability. Aside

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

from the fact that Ford has equaled Asian brands in terms of dependability, the study also found out that Honda is the most dependable auto brand. T

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

his gives the Japanese brand a boost in its reputation as the car company surge forward to increase their brand’s popularity in the United States aut

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

o market.

During the study, the research firm interviewed 31,000 owners of new vehicles. These respondents are asked to list the problems they have

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

et with their new vehicles in the first three months of ownership. The study is only concerned about vehicles released for the 2007 model year. Car

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s and trucks from major automobile brands are considered for the study.

Ford, Lincoln, and Mercury brands collectively are rated almost equal to Nis

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

san and Toyota brands. The study reported that for the Ford, Lincoln, and Mercury brands, there are 1,456 problems encountered per 1,000 vehicles ch

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ecked. For Nissan, the dependability of their vehicles and parts such as their Nissan water pump is rated lower than Ford but almost equal to the U.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

S. brand.

For every 1,000 Nissan vehicles, the study found out that there are 1,456 problems encountered. For Toyota, the study reported that there

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

are 1,453 problems encountered every 1,000 new vehicles. Meanwhile, Honda was found out as the most dependable car brand when new Honda owners repor

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ted 1,313 problems met for every 1,000 vehicles.

For Ford, this study will surely give their reputation a boost. After the recalls of their Escape a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nd the F-Series Super Duty truck, Ford needs to improve their image with regards to dependability. Indeed, Ford is becoming a serious competition fo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

r Asian brands in terms of quality. In the midsize car class, the study found out that there are less problems encountered in the Ford Fusion than t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

he Honda Accord or the Toyota Camry. The most dependable vehicle in Ford’s stable is the Mercury Milan with only 910 problems met per 1,000 vehicles

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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